Warning: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in ..../includes/class_bbcode.php on line 2958

Warning: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in ..../includes/class_bbcode.php on line 2958

Warning: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in ..../includes/class_bbcode.php on line 2958

Warning: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in ..../includes/class_bbcode.php on line 2958

Warning: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in ..../includes/class_bbcode.php on line 2958

Warning: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in ..../includes/class_bbcode.php on line 2958

Warning: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in ..../includes/class_bbcode.php on line 2958

Warning: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in ..../includes/class_bbcode.php on line 2958

Warning: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in ..../includes/class_bbcode.php on line 2958

Warning: preg_replace(): The /e modifier is deprecated, use preg_replace_callback instead in ..../includes/class_bbcode.php on line 2958
- 29


29 37 ... 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
281 290 366

:

  1. #281
      bode
    Jun 2007
    2,818

    :

    :

    : . " " ɡ " " .

    276 " " . " 9" " " .

    " 9" " " . " " " " .


    : .

    "" ɡ ڡ 50% ߡ "" .

    60 5% 6 ڡ .


    : ϡ ǡ . " " "" ɡ . .

    10 600 ʡ 15 10 30 ɡ 60% . " ".

    " "

    10% 15%

    : 60% 2020 70 % 2030 . ֡ . " ... "" ." . .

    7.6 2008 . 70% 5.3 . 2050 .

    895 2008 . .

    12.67 2008 56% . 2010 15 60% . 84% 12% . 75% 10 15% . " ".

    :

    : . "" ɡ 75% 72% 46%. " .. ".

    ɡ ɡ .


    : . " " 42 .

    20 . . .


    ʻ () ߡ ʡ PARP 85% .

    ǡ .


    : . .

    . ɡ .

    . .

    .
    -




    . ϡ ݡ ͡ "" .

    ɡ ǡ .

    ɡ ɡ ɡ ͡ .

    ޡ ѡ ɡ ݡ . .

    " " ɡ ""

    .. ǿ

    ( ): . *

    64 ɡ ǡ . ֡ . : ǿ

    ǡ ɡ . ڡ . .

    *

    * . ɡ . ۡ . ѡ . () osteopenia osteoporosis .

    . ֡ . 1% 40 . . ɡ . ɡ .

    *

    * . ( hypogonadism) . ɡ . 1012 1.9 . ɡ . ( ) .

    nonestrogenic medication . . ɡ 800 1000 ( ).

    ߡ . 1200 () .

    * ȡ ỡ ǻ

  2. #282
      bode
    Jun 2007
    2,818

    Medical


    : "" 10 20 .

    " " . . 40 .







    14 35 .

    - . 14 35 .

    1996 2005 33 661 . "" ɡ .

    ɡ ˡ . ǡ 5 ǡ ɡ . "" .

    (21 ) ӡ ɡ .

    ɡ 66.2 ѡ 70 ˡ 119 ۡ 116 . - - 10.6 9.8 8.6 7.4 . ʡ 32 9 4.9 4.6.

    64

    : / 64 . "" " " ޡ ѡ ɡ ɡ ɡ ".

    " 15 ߡ ". 2008-2009 .

    " ɡ " . " 16 ǡ 8 8 " .

    ɡ .


    63 923 2003 . " 7982 ɡ ".


    "" 4 " ѡ ". " ɡ . : " ɡ ".

    . " ".


    . "" .

    . , . 5% 80% .
    :


    . 1 2 . ɡ .

    56% 84% . 35% 63% 1 10% 27% 2. . 2482 ɡ .

    . 7% (98 ) . ȡ . 1% .

    . .

    " " 15 . . 50 ɡ .

    :

  3. #283
      bode
    Jun 2007
    2,818

    Medical


    : . . .

    50 .. " " .

    : " . .. " ." . " . .



    . ǡ . ͡ ( ).

    70 ɡ : . . ɡ .

    ( Glivec) . ǡ .

    ݡ ɡ ֡ ɡ . . (monoclonale) . .



    : . " " . ɡ ( ) .

    276 " " . " 9" " " . " 9" " " . .


    - - . "" 14 . lobular cancer ɡ . . ǡ 80 . . .

    . 20 . 45 55 . 90 ( ). 1.82 1.

    . . "" ա ϡ ɡ 70 ɡ 10 15 . 80 .



    : 55% . ա " ".

    " 3 " .

    : 8

    : . " " "" .

    25 ɡ 25 . ѡ 55 ѡ 55 . . .

  4. #284
      bode
    Jun 2007
    2,818

    Medical



    . ǡ . " " "" .

    6 . 2954 40 2018 10641 1995 2005.

    30% . " . ". : " . ".



    ڡ . . Ͽ American Association for Cancer research . ǡ Cancer Epidemiology Biomarkers & Prevention .

    ǡ ǡ : . ѡ .

    ˡ ( 1600 ) EPIC . 14 24 . ɡ . . ɡ .

    ɡ ɡ . . ޡ .
    :



    ( ) .

    ɡ . " " ɡ ǡ . .


    . TRASTUZUMAB ( ) RITUXIMAB( NON-HODGKIN-LYMPHOM ) CETUXIMAB

    ɡ . . ( ).



    " . ݡ .


    . . "" "".

    . " 1" . " 1" .

    1 . 1. 1. " " " . ".

    " ". " " . " " ( ) " . "


    , . , .

    ɡ . - 2006- " ". - - , .


    ʡ , . - - 38 42 ǡ 50 55 . ʡ .

    ʡ ɡ 60 .


    ֡ ֡ .

    ѡ . ɡ .

    . 2009 13% ʡ 150 170 44% .
    :

  5. #285
      bode
    Jun 2007
    2,818

    Medical ..

    ..

    * ѻ ɡ . ( ) melanoma ɡ .

    Pigment Cell and Melanoma Research ѡ RXR-alpha ǡ . ǡ ʡ ɡ .

    ""

    : "" 125 107 .

    "" "" . "".

    " ". "" "" "" "" "" .

    "" ɡ "" ʡ ɡ .

    "" "" " " "" " " "" "" "" "" ֡ "" .


    : . .

    " ". 48% 24% . . 1700 300 .

    254 . 50 . ʡ ɡ .



    .

    " ". . . . . . " ".

    " ". 500 50 70 3% . " ". " ".

    : " . ... ". " " 375 . 1 10 .

  6. #286
      bode
    Jun 2007
    2,818

    Medical


    (): ɡ ɡ ǡ . "" ǡ ǡ ǡ ѡ ( ) .

    ( ) ǡ . ǡ ʡ !

    ȡ ɡ ǡ ɡ 10 ǡ 11 67 %. . . . ڡ "" "" . ѡ ɡ .


    *

    . . " 4032" .

    24 32 . . " " .

    "" 4032 . 4 "" . : " . ".




    . ʡ ǡ ɡ .

    . 50 - - . ɡ 50 14 .

    *

    * . ѡ .

    ʡ . ֡ ʡ . 2004 ޡ ɻ ݡ .

    *

    * ǡ . (methyl groups) . ɡ ɻ ϡ ɡ . .

    һ . ɡ ɡ ɡ 100 .

    . ǡ 0.01 . ߡ һ ڡ ҡ 85 . 1600 ( ) .

    *

    * 300 ѡ . . ǡ .

    һ ߻. ʡ ɡ . ҡ ɻ. ܫ Ȼ (Pap test) ɻ. ѡ . .

    *

    * ڡ . : ɻ. ǡ á ɡ . 㻡 . á һ 90 5 10 . : 5 10 ɡ ѻ.

    . ɡ . һ . : . ɻ.
    * һ : *


    .. . () - - . - ( ) - () .



    .

    - . "" 20 2.5 2008 2.1 2002 .

    . . " ".

    . . .

    . .

    . " ." . .


    : " " . " " .

    "" ѡ . .

  7. #287
      bode
    Jun 2007
    2,818

    Medical



    .

    . 75 30%. . . 75 . 16 40 .

    "" () 6000 . . 75 19%. 3 5 24%. 31% . .

    " " " ". " ". . . " 75 ".

    60



    60 . . ߡ .

    . - - ǡ 35 .


    60 ɡ . " " . ߡ " " . ɡ .

    ߡ ֡ " ". ɡ ǡ ߡ .

    60 ǡ " ". 10 ɡ . ǡ . .

    ɡ . ʡ ɡ 60 " " .

    ..

    : 22% 27 . , 1% .

    1800 , "-3", 39%, , .

    , , , , , 31% .



    : " " " " . ʡ "".

    ɡ ǡ . .

    ɡ . ӡ .

  8. #288
      bode
    Jun 2007
    2,818

    Medical


    : ʡ . "" "" " " . - " " " "" ".

    "" . 7 ʡ 27 . . "" ɡ .
    . . .



    . " " . " 1" . 65% 40% . " " "19 13" .

    - - " " " 1". " 1" .

    .
    :


    (): (Johns Hopkins Kimmel Cancer Center) ɡ . ɡ ֡ 10 ֡ . .

    . (ARID1A) "" . . (PPP2R1A) "". ֡ .

    ɡ ʡ . . (ARID1A) ʡ . ɡ ɡ .


    . Carotinoids ѡ . ϻ ʡ . ( ) ʡ . ɡ . ϻ . 600 .

    ɡ ѡ . ɡ ɡ . ɡ ѡ .

    ޡ ϻ ǡ .

    !

    ǡ ɡ .


    ʡ ǡ ǡ ֡ ǡ ɡ . ڡ :

    1 .

    2 ֡ .


    ɡ ( ) ҡ ɡ ϡ .


    ɡ "" " " . ߡ ( ). ( ) ɡ . ɡ ( ) ( ) .


    ǡ ɡ ɡ ʡ ( ) ( ) ǡ ǡ " " . ɡ .


    ʡ ɡ ߡ ߡ ̡ ɡ ء 50% .


    :

    1 .

    2 ǡ ( ) ǡ .

    3 .

  9. #289
      bode
    Jun 2007
    2,818

    Medical


    2003 25 100 .

    1996 2008 9-13 ɡ . 1996-2008 28 .



    : . 1980.

    19 % 26% 12 . 1980 37%.

    1980 62 %. 1978 1982 .

    ..
    " "



    . ѡ 12% .

    . . ɡ ϡ ֡ 1,000 . ʡ .

    ʡ .

    ǡ . 7500 2010 .

    ɡ " . ." .

    ɡ ֡ " ". ".

    "" ɺ 20 . ɡ "" ".

    . " . . ".

    ""- - 2004 . " " . .



    - " " . .



    - .
    - 10% .
    - .
    - .
    - .

    ""

    : ɡ "" . "" "" "".

    ֡ " .

    . 1164 .

    : 150

    : 150 . " " : ȡ ֡ .

    . ֡ .




    . .

    : .

    ɡ .

    .

    : .

    ֡ .

    .

    : ̡ ̡ .

    .

    ѡ .

  10. #290
      bode
    Jun 2007
    2,818

    Medical



    ѡ .

    15 . . 3 . " " .

    "" . : " . ".

    . 2007 . 3 8 . .

    " . ". .

    " ".


    ǡ " " .

    . 1% 1999 2006 1.6% 2001 2006.



    .
    .

    ء . .


    2007 ɡ . ڡ " ̡ ".

    240 . " ʡ " .


    ǡ " ". ӡ - - .

    ѡ .
    :

    50 %

    : , .

    , . , "" "" .

    , , "", " ". 4 , "" .


    : . " " " " 5 ʡ . ʡ .

    "" . ɡ . . .


    " "

    . 39 .

    "" ɡ . " " 30 ޡ .

    13 ǡ 20538 . ߡ 180 . . . 3.6 .

    " "

    : " ". : " ".

    " " ǡ .
    " ". " ȡ ".

  • " " ʪ , , Ӫ ʪ.
  • 17 2006 24 1427 , , , .
  • .
  • , .